Prevention of assay interference in infectious-disease serology tests done on the liaison platform.

نویسندگان

  • Mario Berth
  • Eugene Bosmans
چکیده

Immunoassay interference causing unexpected reactive results in magnetic-microparticle-based assays was detected. A systematic evaluation of Liaison Epstein-Barr virus immunoglobulin M showed that 5% of the positive results (0.4% of tested samples) could be explained by such interference. Adding chemical blocking reagents (polyvinylpyrrolidone and polyvinyl alcohol) to the assay buffers partially prevented this phenomenon.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 15 5  شماره 

صفحات  -

تاریخ انتشار 2008